# Ustekinumab (Ustekinumab-Aekn)

Source: https://ourhealthnetwork.com/drugs/ustekinumab
Data: FDA Orange Book and OpenFDA, refreshed periodically

## What is Ustekinumab?

Ustekinumab (brand name: Ustekinumab-Aekn) is an interleukin antagonists. It is prescribed to treat arthritis, psoriatic, crohn disease. Across the United States, 3,000 doctors prescribe Ustekinumab to approximately 4,000 Medicare patients.

## Brand names

Ustekinumab-Aekn

## Indications

Ustekinumab is prescribed for several conditions including arthritis, psoriatic, crohn disease, among others.

## Conditions treated

- [Arthritis](https://ourhealthnetwork.com/conditions/arthritis)
- [Psoriatic](https://ourhealthnetwork.com/conditions/psoriatic)
- [Crohn Disease](https://ourhealthnetwork.com/conditions/crohn-disease)
- [Psoriasis](https://ourhealthnetwork.com/conditions/psoriasis)
- [Colitis](https://ourhealthnetwork.com/conditions/colitis)
- [Ulcerative](https://ourhealthnetwork.com/conditions/ulcerative)

## Mechanism of action

Ustekinumab products are human IgG1κ monoclonal antibodies that bind with specificity to the p40 protein subunit used by both the IL-12 and IL-23 cytokines. IL-12 and IL-23 are naturally occurring cytokines that are involved in inflammatory and immune responses, such as natural killer cell activation and CD4+ T-cell differentiation and activation.

## Drug classification

- Established Pharmacologic Class: interleukin antagonists
- Route of administration: SUBCUTANEOUS

## Common side effects

fatigue, headache, upper respiratory tract infection

## Sources and disclaimers

- FDA Orange Book and OpenFDA dataset
- This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting, stopping, or changing any medication.

## Related

- [All drugs](https://ourhealthnetwork.com/drugs)
- [Find specialists who prescribe this drug](https://ourhealthnetwork.com/find-doctors)
- [Methodology](https://ourhealthnetwork.com/methodology)