# Tadalafil (Tadalafil)

Source: https://ourhealthnetwork.com/drugs/tadalafil
Data: FDA Orange Book and OpenFDA, refreshed periodically

## What is Tadalafil?

Tadalafil is a phosphodiesterase 5 inhibitor. It is prescribed to treat hypertension, pulmonary, impotence. Across the United States, 7,000 doctors prescribe Tadalafil to approximately 20,000 Medicare patients.

## Brand names

Tadalafil

## Indications

Tadalafil is prescribed for several conditions including hypertension, pulmonary, impotence, among others.

## Conditions treated

- [Hypertension](https://ourhealthnetwork.com/conditions/hypertension)
- [Pulmonary](https://ourhealthnetwork.com/conditions/pulmonary)
- [Impotence](https://ourhealthnetwork.com/conditions/impotence)
- [Vasculogenic](https://ourhealthnetwork.com/conditions/vasculogenic)

## Mechanism of action

Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells.

## Drug classification

- Established Pharmacologic Class: Phosphodiesterase 5 Inhibitor [EPC]
- Mechanism of Action class: Phosphodiesterase 5 Inhibitors [MoA]
- Route of administration: ORAL

## Common side effects

back pain, dyspepsia, flushing, headache, myalgia, nasal congestion, pain in limb ( 6

## Sources and disclaimers

- FDA Orange Book and OpenFDA dataset
- This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting, stopping, or changing any medication.

## Related

- [All drugs](https://ourhealthnetwork.com/drugs)
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- [Methodology](https://ourhealthnetwork.com/methodology)