# Sumatriptan Succinate (Sumatriptan)

Source: https://ourhealthnetwork.com/drugs/sumatriptan-succinate
Data: FDA Orange Book and OpenFDA, refreshed periodically

## What is Sumatriptan Succinate?

Sumatriptan Succinate (brand name: Sumatriptan) is a selective serotonin receptor agonists. It is prescribed to treat cluster headache, migraine disorders. Across the United States, 55,000 doctors prescribe Sumatriptan to approximately 68,000 Medicare patients.

## Brand names

Sumatriptan

## Indications

Sumatriptan Succinate is prescribed for the treatment of cluster headache and migraine disorders.

## Conditions treated

- [Cluster Headache](https://ourhealthnetwork.com/conditions/cluster-headache)
- [Migraine Disorders](https://ourhealthnetwork.com/conditions/migraine-disorders)

## Mechanism of action

Sumatriptan binds with high affinity to human cloned 5-HT 1B/1D receptors. Sumatriptan presumably exerts its therapeutic effects in the treatment of migraine and cluster headaches through agonist effects at the 5-HT 1B/1D receptors on intracranial blood vessels and sensory nerves of the trigeminal system, which result in cranial vessel constriction and inhibition of pro-inflammatory neuropeptide r

## Drug classification

- Established Pharmacologic Class: selective serotonin receptor agonists
- Route of administration: SUBCUTANEOUS

## Common side effects

burning sensation, dizziness/vertigo, feeling of heaviness, feeling of tightness, flushing, injection site reactions, numbness (6, pressure sensation

## Sources and disclaimers

- FDA Orange Book and OpenFDA dataset
- This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting, stopping, or changing any medication.

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