# Rosuvastatin Calcium (Crestor)

Source: https://ourhealthnetwork.com/drugs/rosuvastatin-calcium
Data: FDA Orange Book and OpenFDA, refreshed periodically

## What is Rosuvastatin Calcium?

Rosuvastatin Calcium (brand name: Crestor) is a HMG-CoA reductase inhibitor (statin). It is prescribed to treat hypertriglyceridemia, coronary artery disease, hypercholesterolemia. Across the United States, 243,000 doctors prescribe Rosuvastatin to approximately 7.7 million Medicare patients, making it one of the top 10 most prescribed drugs in America.

## Brand names

Crestor

## Indications

Rosuvastatin Calcium is prescribed for several conditions including hypertriglyceridemia, coronary artery disease, hypercholesterolemia, among others.

## Conditions treated

- [Hypertriglyceridemia](https://ourhealthnetwork.com/conditions/hypertriglyceridemia)
- [Coronary Artery Disease](https://ourhealthnetwork.com/conditions/coronary-artery-disease)
- [Hypercholesterolemia](https://ourhealthnetwork.com/conditions/hypercholesterolemia)
- [Hyperlipoproteinemias](https://ourhealthnetwork.com/conditions/hyperlipoproteinemias)

## Mechanism of action

Rosuvastatin is an inhibitor of HMG-CoA reductase, an enzyme that produces 3‑hydroxy‑3‑methylglutaryl coenzyme A to mevalonate, a precursor of cholesterol.

## Drug classification

- Established Pharmacologic Class: HMG-CoA reductase inhibitors (statins)
- Route of administration: ORAL

## Common side effects

headache, muscle pain, abdominal pain, nausea, weakness

## Sources and disclaimers

- FDA Orange Book and OpenFDA dataset
- This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting, stopping, or changing any medication.

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