# Prucalopride Succinate (Prucalopride)

Source: https://ourhealthnetwork.com/drugs/prucalopride-succinate
Data: FDA Orange Book and OpenFDA, refreshed periodically

## What is Prucalopride Succinate?

Prucalopride Succinate (brand name: Prucalopride) is a serotonin receptor agonist. It is prescribed to treat constipation. Across the United States, 2,000 doctors prescribe Prucalopride to approximately 3,000 Medicare patients.

## Brand names

Prucalopride

## Indications

Prucalopride Succinate is primarily prescribed for the treatment of constipation.

## Conditions treated

- [Constipation](https://ourhealthnetwork.com/conditions/constipation)

## Mechanism of action

Prucalopride, a selective serotonin type 4 (5-HT 4 ) receptor agonist, is a gastrointestinal (GI) prokinetic agent that stimulates colonic peristalsis (high-amplitude propagating contractions [HAPCs]), which increases bowel motility. Prucalopride was devoid of effects mediated via 5-HT 2A , 5-HT 2B , 5-HT 3 , motilin or CCK-A receptors in vitro at concentrations exceeding 5-HT 4 receptor affinity

## Drug classification

- Established Pharmacologic Class: serotonin receptor agonists
- Route of administration: ORAL

## Common side effects

abdominal distension, abdominal pain, and white, diarrhea, dizziness, fatigue, flatulence, headache

## Sources and disclaimers

- FDA Orange Book and OpenFDA dataset
- This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting, stopping, or changing any medication.

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