# Memantine Hcl (Memantine Hydrochloride)

Source: https://ourhealthnetwork.com/drugs/memantine-hcl
Data: FDA Orange Book and OpenFDA, refreshed periodically

## What is Memantine Hcl?

Memantine Hcl (brand name: Memantine Hydrochloride) is a cholinesterase inhibitor. It is prescribed to treat alzheimer disease. Across the United States, 83,000 doctors prescribe Memantine to approximately 739,000 Medicare patients.

## Brand names

Memantine Hydrochloride

## Indications

Memantine Hcl is primarily prescribed for the treatment of alzheimer disease.

## Conditions treated

- [Alzheimer Disease](https://ourhealthnetwork.com/conditions/alzheimer-disease)

## Mechanism of action

Persistent activation of central nervous system N-methyl-D-aspartate (NMDA) receptors by the excitatory amino acid glutamate has been hypothesized to contribute to the symptomatology of Alzheimer’s disease. Memantine is postulated to exert its therapeutic effect through its action as a low to moderate affinity uncompetitive (open-channel) NMDA receptor antagonist which binds preferentially to the

## Drug classification

- Established Pharmacologic Class: cholinesterase inhibitors
- Route of administration: ORAL

## Common side effects

as in the placebo group, confusion and constipation, dizziness, headache

## Sources and disclaimers

- FDA Orange Book and OpenFDA dataset
- This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting, stopping, or changing any medication.

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