# Lenvatinib Mesylate (Lenvima)

Source: https://ourhealthnetwork.com/drugs/lenvatinib-mesylate
Data: FDA Orange Book and OpenFDA, refreshed periodically

## What is Lenvatinib Mesylate?

Lenvatinib Mesylate (brand name: Lenvima) is a kinase inhibitor. It is prescribed to treat carcinoma, renal cell, thyroid neoplasms. Across the United States, 898 doctors prescribe Lenvatinib to approximately 297 Medicare patients.

## Brand names

Lenvima

## Indications

Lenvatinib Mesylate is prescribed for the treatment of carcinoma, renal cell and thyroid neoplasms.

## Conditions treated

- [Carcinoma](https://ourhealthnetwork.com/conditions/carcinoma)
- [Renal Cell](https://ourhealthnetwork.com/conditions/renal-cell)
- [Thyroid Neoplasms](https://ourhealthnetwork.com/conditions/thyroid-neoplasms)

## Mechanism of action

Lenvatinib is a kinase inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). Lenvatinib inhibits other kinases that have been implicated in pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellular functions, including fibroblast growth factor (FGF) receptors FGFR

## Drug classification

- Established Pharmacologic Class: Kinase Inhibitor [EPC]
- Mechanism of Action class: Receptor Tyrosine Kinase Inhibitors [MoA]
- Route of administration: ORAL

## Common side effects

of whom 20 (31%), resulting in dose reduction or interruption of LENVIMA were diarrhea (26%), treated group were diarrhea (21%), fatigue (18%), 2 increased ALT or AST was reported in 64 (18%), adverse reactions resulting in dose reduction of LENVIMA were hypertension (18%), hypertension (17%), resulting in dose reductions of LENVIMA were hypertension (13%)

## Sources and disclaimers

- FDA Orange Book and OpenFDA dataset
- This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting, stopping, or changing any medication.

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