# Hydrochlorothiazide (Microzide, HydroDIURIL)

Source: https://ourhealthnetwork.com/drugs/hydrochlorothiazide
Data: FDA Orange Book and OpenFDA, refreshed periodically

## What is Hydrochlorothiazide?

Hydrochlorothiazide (brand name: Microzide, HydroDIURIL) is a thiazide diuretic. It is prescribed to treat hypertension, nephrotic syndrome, edema. Across the United States, 243,000 doctors prescribe Hydrochlorothiazide to approximately 5.1 million Medicare patients, making it one of the 50 most prescribed drugs in America.

## Brand names

Microzide, HydroDIURIL

## Indications

Hydrochlorothiazide is prescribed for several conditions including hypertension, nephrotic syndrome, edema, among others.

## Conditions treated

- [Hypertension](https://ourhealthnetwork.com/conditions/hypertension)
- [Nephrotic Syndrome](https://ourhealthnetwork.com/conditions/nephrotic-syndrome)
- [Edema](https://ourhealthnetwork.com/conditions/edema)
- [Heart Failure](https://ourhealthnetwork.com/conditions/heart-failure)

## Mechanism of action

Lisinopril inhibits ACE (a protein that raises blood pressure) in human subjects and animals. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II.

## Drug classification

- Established Pharmacologic Class: Thiazide Diuretic [EPC]
- Route of administration: ORAL

## Common side effects

and orthostatic effects, cough, dizziness, fatigue, headache

## Sources and disclaimers

- FDA Orange Book and OpenFDA dataset
- This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting, stopping, or changing any medication.

## Related

- [All drugs](https://ourhealthnetwork.com/drugs)
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- [Methodology](https://ourhealthnetwork.com/methodology)