# Guselkumab (Tremfya)

Source: https://ourhealthnetwork.com/drugs/guselkumab
Data: FDA Orange Book and OpenFDA, refreshed periodically

## What is Guselkumab?

Guselkumab (brand name: Tremfya) is an interleukin-23 antagonist. It is prescribed to treat psoriasis. Across the United States, 849 doctors prescribe Guselkumab to approximately 245 Medicare patients.

## Brand names

Tremfya

## Indications

Guselkumab is primarily prescribed for the treatment of psoriasis.

## Conditions treated

- [Psoriasis](https://ourhealthnetwork.com/conditions/psoriasis)

## Mechanism of action

Guselkumab is a human monoclonal IgG1λ antibody that selectively binds to the p19 subunit of interleukin 23 (IL-23) and inhibits its interaction with the IL-23 receptor. IL-23 is a naturally occurring cytokine that is involved in normal inflammatory and immune responses.

## Drug classification

- Established Pharmacologic Class: Interleukin-23 Antagonist [EPC]
- Mechanism of Action class: Interleukin-23 Antagonists [MoA]
- Route of administration: SUBCUTANEOUS

## Common side effects

abdominal pain, arthralgia, bronchitis, diarrhea, fatigue, headache, rash, upper respiratory tract infection

## Sources and disclaimers

- FDA Orange Book and OpenFDA dataset
- This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting, stopping, or changing any medication.

## Related

- [All drugs](https://ourhealthnetwork.com/drugs)
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- [Methodology](https://ourhealthnetwork.com/methodology)