# Dabigatran Etexilate Mesylate (Dabigatran Etexilate)

Source: https://ourhealthnetwork.com/drugs/dabigatran-etexilate-mesylate
Data: FDA Orange Book and OpenFDA, refreshed periodically

## What is Dabigatran Etexilate Mesylate?

Dabigatran Etexilate Mesylate (brand name: Dabigatran Etexilate) is a prescription medication. Across the United States, 12,000 doctors prescribe Dabigatran to approximately 126,000 Medicare patients.

## Brand names

Dabigatran Etexilate

## Indications

Dabigatran etexilate capsules are a direct thrombin inhibitor indicated: • To reduce the risk of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation  • For the treatment of deep venous thrombosis (DVT) and pulmonary embolism (PE) in adult patients who have been treated with a parenteral anticoagulant for 5 to 10 days  • To reduce the risk of recurrence of DVT and PE in adult patients who have been previously treated  • For the prophylaxis of DVT and PE in adult p

## Conditions treated

- [Atrial Fibrillation](https://ourhealthnetwork.com/conditions/atrial-fibrillation)
- [Stroke](https://ourhealthnetwork.com/conditions/stroke)
- [Venous Thrombosis](https://ourhealthnetwork.com/conditions/venous-thrombosis)
- [Pulmonary Embolism](https://ourhealthnetwork.com/conditions/pulmonary-embolism)

## Mechanism of action

Dabigatran and its acyl glucuronides are competitive, direct thrombin inhibitors. Because thrombin (serine protease) enables the conversion of fibrinogen into fibrin during the coagulation cascade, its inhibition prevents the development of a thrombus.

## Drug classification

- Established Pharmacologic Class: Prescription Medication
- Route of administration: ORAL

## Common side effects

The majority of the patients were white (96.1%), The majority of the patients were white (87.7%), and half the patients were male (50%), 373 (26.2), 22 (24), 21 (23), 567 (22.7), Any bleeding 38 (22)

## Sources and disclaimers

- FDA Orange Book and OpenFDA dataset
- This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting, stopping, or changing any medication.

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