# Anakinra (Kineret)

Source: https://ourhealthnetwork.com/drugs/anakinra
Data: FDA Orange Book and OpenFDA, refreshed periodically

## What is Anakinra?

Anakinra (brand name: Kineret) is an interleukin-1 receptor antagonist. It is prescribed to treat arthritis, rheumatoid, cryopyrin-associated periodic syndromes.

## Brand names

Kineret

## Indications

Anakinra is prescribed for the treatment of arthritis, rheumatoid and cryopyrin-associated periodic syndromes.

## Conditions treated

- [Arthritis](https://ourhealthnetwork.com/conditions/arthritis)
- [Rheumatoid](https://ourhealthnetwork.com/conditions/rheumatoid)
- [Cryopyrin-Associated Periodic Syndromes](https://ourhealthnetwork.com/conditions/cryopyrin-associated-periodic-syndromes)

## Mechanism of action

KINERET blocks the biologic activity of IL-1 alpha and beta by competitively inhibiting IL-1 binding to the interleukin-1 type I receptor (IL-1RI), which is expressed in a wide variety of tissues and organs. IL-1 production is induced in response to inflammatory stimuli and mediates various physiologic responses including inflammatory and immunological responses.

## Drug classification

- Established Pharmacologic Class: Interleukin-1 Receptor Antagonist [EPC]
- Mechanism of Action class: Interleukin 1 Receptor Antagonists [MoA]
- Route of administration: SUBCUTANEOUS

## Common side effects

abdominal pain ( 6, arthralgia, diarrhea, flu like-symptoms, headache, injection site reaction, nausea, sinusitis

## Sources and disclaimers

- FDA Orange Book and OpenFDA dataset
- This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting, stopping, or changing any medication.

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